Nguru’s extensive career includes pivotal roles with organizations such as the New York State Black Gay Network, where he supported HIV-related services for Black gay men, and the Audre Lorde Project, New York City’s first LGBTIQ community center for people of color. His commitment to global LGBTIQ+ advocacy began in 1998 as an International Grants Panelist for the Astraea Lesbian Foundation for Justice, where he later served as an International Advisory Member. He also contributed to the Open Society Foundation’s LGBTI Rights Initiative Advisory Committee, further solidifying his impact on global human rights.

In 2008, Nguru was selected to review Kenya’s National AIDS Strategic Plan (KNASP 2) and provide recommendations for KNASP 3, shaping the country’s HIV response. That same year, he played a key role in establishing UHAI-EASHRI, the East African Health and Rights Initiative, which supports activism around sexuality, health, and human rights in East Africa. Nguru has also served on the National Key Population Advocacy Task Force in Kenya and the Eastern and Southern Africa Regional Think-Tank on HIV, Health, and Social Justice, convened by UNAIDS to advance human rights and social justice in the context of HIV.

A prolific writer, Nguru authored “We’ve Been Here,” a ground-breaking compilation of stories from older LGBTIQ+ Kenyans.

Today, he continues to advise and support key population initiatives, including the Key Populations Coalition, Team No Sleep (an LGBTIQ+ refugee organization), and the Tanzania Transgender Initiative. Through his unwavering dedication, Nguru has become a cornerstone of public health and human rights advocacy, driving transformative change for marginalized communities worldwide.